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Standardized Electrolyte Supplementation and Fluid Management Improves Survival During Amphotericin Therapy for Cryptococcal Meningitis in Resource-Limited Settings
BACKGROUND: Amphotericin B is the preferred treatment for cryptococcal meningitis, but it has cumulative severe side effects, including nephrotoxicity, hypokalemia, and hypomagnesemia. Amphotericin-induced severe hypokalemia may predispose the patient to cardiac arrhythmias and death, and there is...
Autores principales: | Bahr, Nathan C., Rolfes, Melissa A., Musubire, Abdu, Nabeta, Henry, Williams, Darlisha A., Rhein, Joshua, Kambugu, Andrew, Meya, David B., Boulware, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281785/ https://www.ncbi.nlm.nih.gov/pubmed/25734140 http://dx.doi.org/10.1093/ofid/ofu070 |
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