Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis

No clinical trials have investigated the use of ceftaroline fosamil for salvage therapy of methicillin-resistant Staphylococcus aureus bacteremia and endocarditis. We report data on 29 patients who received ceftaroline ± another antimicrobial for this indication. Ninety percent of patients had micro...

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Detalles Bibliográficos
Autores principales: Fabre, Valeria, Ferrada, Marcela, Buckel, Whitney R., Avdic, Edina, Cosgrove, Sara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281789/
https://www.ncbi.nlm.nih.gov/pubmed/25734118
http://dx.doi.org/10.1093/ofid/ofu046
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author Fabre, Valeria
Ferrada, Marcela
Buckel, Whitney R.
Avdic, Edina
Cosgrove, Sara E.
author_facet Fabre, Valeria
Ferrada, Marcela
Buckel, Whitney R.
Avdic, Edina
Cosgrove, Sara E.
author_sort Fabre, Valeria
collection PubMed
description No clinical trials have investigated the use of ceftaroline fosamil for salvage therapy of methicillin-resistant Staphylococcus aureus bacteremia and endocarditis. We report data on 29 patients who received ceftaroline ± another antimicrobial for this indication. Ninety percent of patients had microbiologic cure and 31% had treatment success with a median follow-up of 6 months.
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spelling pubmed-42817892015-03-02 Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis Fabre, Valeria Ferrada, Marcela Buckel, Whitney R. Avdic, Edina Cosgrove, Sara E. Open Forum Infect Dis Brief Reports No clinical trials have investigated the use of ceftaroline fosamil for salvage therapy of methicillin-resistant Staphylococcus aureus bacteremia and endocarditis. We report data on 29 patients who received ceftaroline ± another antimicrobial for this indication. Ninety percent of patients had microbiologic cure and 31% had treatment success with a median follow-up of 6 months. Oxford University Press 2014-07-08 /pmc/articles/PMC4281789/ /pubmed/25734118 http://dx.doi.org/10.1093/ofid/ofu046 Text en © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Fabre, Valeria
Ferrada, Marcela
Buckel, Whitney R.
Avdic, Edina
Cosgrove, Sara E.
Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis
title Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis
title_full Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis
title_fullStr Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis
title_full_unstemmed Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis
title_short Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis
title_sort ceftaroline in combination with trimethoprim-sulfamethoxazole for salvage therapy of methicillin-resistant staphylococcus aureus bacteremia and endocarditis
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281789/
https://www.ncbi.nlm.nih.gov/pubmed/25734118
http://dx.doi.org/10.1093/ofid/ofu046
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