Varicella Zoster Virus Pneumonitis and Brainstem Encephalitis Without Skin Rash in an Immunocompetent Adult

Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous s...

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Detalles Bibliográficos
Autores principales: Nandhagopal, Ramachandiran, Khmeleva, Nelly, Jayakrishnan, B., White, Teresa, Al Azri, Faisal, George, Jojy, Heintzman, Anna, Al Zeedy, Khalfan, Rorke-Adams, Lucy, Gujjar, Arunodaya R., Schmid, D. Scott, Al-Asmi, Abdullah, Nagel, Maria A., Jacob, Poovathoor Chacko, Gilden, Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281813/
https://www.ncbi.nlm.nih.gov/pubmed/25734134
http://dx.doi.org/10.1093/ofid/ofu064
Descripción
Sumario:Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.

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