Electron Cryo‐Microscopy of TPPS(4)⋅2HCl Tubes Reveals a Helical Organisation Explaining the Origin of their Chirality

A widely studied achiral porphyrin, which is highly soluble in aqueous solutions (TPPS(4)), is shown to self‐assemble into helical nanotubes. These were imaged by electron cryo‐microscopy and a state‐of‐the‐art image analysis allows building a map at ∼5 Å resolution, one of the highest obtained so f...

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Detalles Bibliográficos
Autores principales: Short, Judith M., Berriman, John A., Kübel, Christian, El‐Hachemi, Zoubir, Naubron, Jean‐Valère, Balaban, Teodor Silviu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2013
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281918/
https://www.ncbi.nlm.nih.gov/pubmed/23908093
http://dx.doi.org/10.1002/cphc.201300606
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author Short, Judith M.
Berriman, John A.
Kübel, Christian
El‐Hachemi, Zoubir
Naubron, Jean‐Valère
Balaban, Teodor Silviu
author_facet Short, Judith M.
Berriman, John A.
Kübel, Christian
El‐Hachemi, Zoubir
Naubron, Jean‐Valère
Balaban, Teodor Silviu
author_sort Short, Judith M.
collection PubMed
description A widely studied achiral porphyrin, which is highly soluble in aqueous solutions (TPPS(4)), is shown to self‐assemble into helical nanotubes. These were imaged by electron cryo‐microscopy and a state‐of‐the‐art image analysis allows building a map at ∼5 Å resolution, one of the highest obtained so far for molecular materials. The authors were able to trace the apparent symmetry breaking to existing nuclei in the “as received samples”, while carefully purified samples show that both handnesses occur in equal amounts.[Image: see text]
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spelling pubmed-42819182015-01-15 Electron Cryo‐Microscopy of TPPS(4)⋅2HCl Tubes Reveals a Helical Organisation Explaining the Origin of their Chirality Short, Judith M. Berriman, John A. Kübel, Christian El‐Hachemi, Zoubir Naubron, Jean‐Valère Balaban, Teodor Silviu Chemphyschem Communications A widely studied achiral porphyrin, which is highly soluble in aqueous solutions (TPPS(4)), is shown to self‐assemble into helical nanotubes. These were imaged by electron cryo‐microscopy and a state‐of‐the‐art image analysis allows building a map at ∼5 Å resolution, one of the highest obtained so far for molecular materials. The authors were able to trace the apparent symmetry breaking to existing nuclei in the “as received samples”, while carefully purified samples show that both handnesses occur in equal amounts.[Image: see text] WILEY‐VCH Verlag 2013-07-31 2013-10-01 /pmc/articles/PMC4281918/ /pubmed/23908093 http://dx.doi.org/10.1002/cphc.201300606 Text en © 2013 The Authors. Published by Wiley‐VCH Verlag GmbH & Co. KGaA. https://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Short, Judith M.
Berriman, John A.
Kübel, Christian
El‐Hachemi, Zoubir
Naubron, Jean‐Valère
Balaban, Teodor Silviu
Electron Cryo‐Microscopy of TPPS(4)⋅2HCl Tubes Reveals a Helical Organisation Explaining the Origin of their Chirality
title Electron Cryo‐Microscopy of TPPS(4)⋅2HCl Tubes Reveals a Helical Organisation Explaining the Origin of their Chirality
title_full Electron Cryo‐Microscopy of TPPS(4)⋅2HCl Tubes Reveals a Helical Organisation Explaining the Origin of their Chirality
title_fullStr Electron Cryo‐Microscopy of TPPS(4)⋅2HCl Tubes Reveals a Helical Organisation Explaining the Origin of their Chirality
title_full_unstemmed Electron Cryo‐Microscopy of TPPS(4)⋅2HCl Tubes Reveals a Helical Organisation Explaining the Origin of their Chirality
title_short Electron Cryo‐Microscopy of TPPS(4)⋅2HCl Tubes Reveals a Helical Organisation Explaining the Origin of their Chirality
title_sort electron cryo‐microscopy of tpps(4)⋅2hcl tubes reveals a helical organisation explaining the origin of their chirality
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281918/
https://www.ncbi.nlm.nih.gov/pubmed/23908093
http://dx.doi.org/10.1002/cphc.201300606
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