Organizing knowledge to enable personalization of medicine in cancer

Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genom...

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Detalles Bibliográficos
Autores principales: Good, Benjamin M, Ainscough, Benjamin J, McMichael, Josh F, Su, Andrew I, Griffith, Obi L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281950/
https://www.ncbi.nlm.nih.gov/pubmed/25222080
http://dx.doi.org/10.1186/s13059-014-0438-7
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author Good, Benjamin M
Ainscough, Benjamin J
McMichael, Josh F
Su, Andrew I
Griffith, Obi L
author_facet Good, Benjamin M
Ainscough, Benjamin J
McMichael, Josh F
Su, Andrew I
Griffith, Obi L
author_sort Good, Benjamin M
collection PubMed
description Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer.
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spelling pubmed-42819502015-01-03 Organizing knowledge to enable personalization of medicine in cancer Good, Benjamin M Ainscough, Benjamin J McMichael, Josh F Su, Andrew I Griffith, Obi L Genome Biol Opinion Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer. BioMed Central 2014-08-27 2014 /pmc/articles/PMC4281950/ /pubmed/25222080 http://dx.doi.org/10.1186/s13059-014-0438-7 Text en © Good et al.; licensee BioMed Central Ltd. 2014 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Opinion
Good, Benjamin M
Ainscough, Benjamin J
McMichael, Josh F
Su, Andrew I
Griffith, Obi L
Organizing knowledge to enable personalization of medicine in cancer
title Organizing knowledge to enable personalization of medicine in cancer
title_full Organizing knowledge to enable personalization of medicine in cancer
title_fullStr Organizing knowledge to enable personalization of medicine in cancer
title_full_unstemmed Organizing knowledge to enable personalization of medicine in cancer
title_short Organizing knowledge to enable personalization of medicine in cancer
title_sort organizing knowledge to enable personalization of medicine in cancer
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281950/
https://www.ncbi.nlm.nih.gov/pubmed/25222080
http://dx.doi.org/10.1186/s13059-014-0438-7
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