Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance

DNA fragments released from cancer cells into the blood can be used to generate molecular profiles of tumors. Non-invasive 'liquid biopsies' can be used to monitor minimal residual disease and detect the emergence of drug resistance.

Detalles Bibliográficos
Autores principales: Siravegna, Giulia, Bardelli, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281953/
https://www.ncbi.nlm.nih.gov/pubmed/25222559
http://dx.doi.org/10.1186/s13059-014-0449-4
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author Siravegna, Giulia
Bardelli, Alberto
author_facet Siravegna, Giulia
Bardelli, Alberto
author_sort Siravegna, Giulia
collection PubMed
description DNA fragments released from cancer cells into the blood can be used to generate molecular profiles of tumors. Non-invasive 'liquid biopsies' can be used to monitor minimal residual disease and detect the emergence of drug resistance.
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spelling pubmed-42819532015-01-03 Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance Siravegna, Giulia Bardelli, Alberto Genome Biol Review DNA fragments released from cancer cells into the blood can be used to generate molecular profiles of tumors. Non-invasive 'liquid biopsies' can be used to monitor minimal residual disease and detect the emergence of drug resistance. BioMed Central 2014-08-30 2014 /pmc/articles/PMC4281953/ /pubmed/25222559 http://dx.doi.org/10.1186/s13059-014-0449-4 Text en © Siravegna and Bardelli; licensee BioMed Central 2014 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Siravegna, Giulia
Bardelli, Alberto
Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance
title Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance
title_full Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance
title_fullStr Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance
title_full_unstemmed Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance
title_short Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance
title_sort genotyping cell-free tumor dna in the blood to detect residual disease and drug resistance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281953/
https://www.ncbi.nlm.nih.gov/pubmed/25222559
http://dx.doi.org/10.1186/s13059-014-0449-4
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