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Genotyping cell-free tumor DNA in the blood to detect residual disease and drug resistance

DNA fragments released from cancer cells into the blood can be used to generate molecular profiles of tumors. Non-invasive 'liquid biopsies' can be used to monitor minimal residual disease and detect the emergence of drug resistance.

Detalles Bibliográficos
Autores principales: Siravegna, Giulia, Bardelli, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281953/
https://www.ncbi.nlm.nih.gov/pubmed/25222559
http://dx.doi.org/10.1186/s13059-014-0449-4