One patient, two lesions, two oncogenic drivers of gastric cancer

Deep-sequencing of a primary tumor and metastasis from a single patient, and functional validation in culture, reveals that TGFBR2 and FGFR2 act as drivers of gastric cancer.

Detalles Bibliográficos
Autores principales: Alsinet, Clara, Ranzani, Marco, Adams, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281955/
https://www.ncbi.nlm.nih.gov/pubmed/25222187
http://dx.doi.org/10.1186/s13059-014-0444-9
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author Alsinet, Clara
Ranzani, Marco
Adams, David J
author_facet Alsinet, Clara
Ranzani, Marco
Adams, David J
author_sort Alsinet, Clara
collection PubMed
description Deep-sequencing of a primary tumor and metastasis from a single patient, and functional validation in culture, reveals that TGFBR2 and FGFR2 act as drivers of gastric cancer.
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spelling pubmed-42819552015-01-03 One patient, two lesions, two oncogenic drivers of gastric cancer Alsinet, Clara Ranzani, Marco Adams, David J Genome Biol Research Highlight Deep-sequencing of a primary tumor and metastasis from a single patient, and functional validation in culture, reveals that TGFBR2 and FGFR2 act as drivers of gastric cancer. BioMed Central 2014-08-27 2014 /pmc/articles/PMC4281955/ /pubmed/25222187 http://dx.doi.org/10.1186/s13059-014-0444-9 Text en © Alsinet et al.; licensee BioMed Central 2014 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Highlight
Alsinet, Clara
Ranzani, Marco
Adams, David J
One patient, two lesions, two oncogenic drivers of gastric cancer
title One patient, two lesions, two oncogenic drivers of gastric cancer
title_full One patient, two lesions, two oncogenic drivers of gastric cancer
title_fullStr One patient, two lesions, two oncogenic drivers of gastric cancer
title_full_unstemmed One patient, two lesions, two oncogenic drivers of gastric cancer
title_short One patient, two lesions, two oncogenic drivers of gastric cancer
title_sort one patient, two lesions, two oncogenic drivers of gastric cancer
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281955/
https://www.ncbi.nlm.nih.gov/pubmed/25222187
http://dx.doi.org/10.1186/s13059-014-0444-9
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AT ranzanimarco onepatienttwolesionstwooncogenicdriversofgastriccancer
AT adamsdavidj onepatienttwolesionstwooncogenicdriversofgastriccancer

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