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Translating genomics research into control of tuberculosis: lessons learned and future prospects
Genomics research has enabled crucial insights into the adaptive evolution of Mycobacterium tuberculosis as an obligate human pathogen. Here, we highlight major recent advances and evaluate the potential for genomics approaches to inform tuberculosis control efforts in high-burden settings.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282010/ https://www.ncbi.nlm.nih.gov/pubmed/25408168 http://dx.doi.org/10.1186/s13059-014-0514-z |
| _version_ | 1782351055710846976 |
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| author | Warner, Digby F Mizrahi, Valerie |
| author_facet | Warner, Digby F Mizrahi, Valerie |
| author_sort | Warner, Digby F |
| collection | PubMed |
| description | Genomics research has enabled crucial insights into the adaptive evolution of Mycobacterium tuberculosis as an obligate human pathogen. Here, we highlight major recent advances and evaluate the potential for genomics approaches to inform tuberculosis control efforts in high-burden settings. |
| format | Online Article Text |
| id | pubmed-4282010 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-42820102015-01-03 Translating genomics research into control of tuberculosis: lessons learned and future prospects Warner, Digby F Mizrahi, Valerie Genome Biol Review Genomics research has enabled crucial insights into the adaptive evolution of Mycobacterium tuberculosis as an obligate human pathogen. Here, we highlight major recent advances and evaluate the potential for genomics approaches to inform tuberculosis control efforts in high-burden settings. BioMed Central 2014-11-07 2014 /pmc/articles/PMC4282010/ /pubmed/25408168 http://dx.doi.org/10.1186/s13059-014-0514-z Text en © Warner and Mizrahi; licensee BioMed Central Ltd. 2014 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Review Warner, Digby F Mizrahi, Valerie Translating genomics research into control of tuberculosis: lessons learned and future prospects |
| title | Translating genomics research into control of tuberculosis: lessons learned and future prospects |
| title_full | Translating genomics research into control of tuberculosis: lessons learned and future prospects |
| title_fullStr | Translating genomics research into control of tuberculosis: lessons learned and future prospects |
| title_full_unstemmed | Translating genomics research into control of tuberculosis: lessons learned and future prospects |
| title_short | Translating genomics research into control of tuberculosis: lessons learned and future prospects |
| title_sort | translating genomics research into control of tuberculosis: lessons learned and future prospects |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282010/ https://www.ncbi.nlm.nih.gov/pubmed/25408168 http://dx.doi.org/10.1186/s13059-014-0514-z |
| work_keys_str_mv | AT warnerdigbyf translatinggenomicsresearchintocontroloftuberculosislessonslearnedandfutureprospects AT mizrahivalerie translatinggenomicsresearchintocontroloftuberculosislessonslearnedandfutureprospects |