Cargando…
Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways
A key step of mitosis is the congression of chromosomes to the spindle equator. Congression is driven by at least two distinct mechanisms: (1) kinetochores slide along the microtubule lattice using the plus-end directed CENP-E motor, and (2) kinetochores biorientating near the pole move to the equat...
Autores principales: | Bancroft, James, Auckland, Philip, Samora, Catarina P., McAinsh, Andrew D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282051/ https://www.ncbi.nlm.nih.gov/pubmed/25395579 http://dx.doi.org/10.1242/jcs.163659 |
Ejemplares similares
-
CENP-F stabilizes kinetochore-microtubule attachments and limits dynein stripping of corona cargoes
por: Auckland, Philip, et al.
Publicado: (2020) -
Impaired CENP-E Function Renders Large Chromosomes More Vulnerable to Congression Failure
por: Tovini, Laura, et al.
Publicado: (2019) -
Step-Wise Assembly, Maturation and Dynamic Behavior of the Human CENP-P/O/R/Q/U Kinetochore Sub-Complex
por: Eskat, Anja, et al.
Publicado: (2012) -
Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment
por: Auckland, Philip, et al.
Publicado: (2017) -
Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80
por: Pesenti, Marion E., et al.
Publicado: (2018)