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CHOPPI: A Web Tool for the Analysis of Immunogenicity Risk from Host Cell Proteins in CHO-Based Protein Production

Despite high quality standards and continual process improvements in manufacturing, host cell protein (HCP) process impurities remain a substantial risk for biological products. Even at low levels, residual HCPs can induce a detrimental immune response compromising the safety and efficacy of a biolo...

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Detalles Bibliográficos
Autores principales:	Bailey-Kellogg, Chris, Gutiérrez, Andres H, Moise, Leonard, Terry, Frances, Martin, William D, De Groot, Anne S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282101/ https://www.ncbi.nlm.nih.gov/pubmed/24888712 http://dx.doi.org/10.1002/bit.25286

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