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FANCJ promotes DNA synthesis through G-quadruplex structures

Our genome contains many G-rich sequences, which have the propensity to fold into stable secondary DNA structures called G4 or G-quadruplex structures. These structures have been implicated in cellular processes such as gene regulation and telomere maintenance. However, G4 sequences are prone to mut...

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Detalles Bibliográficos
Autores principales: Castillo Bosch, Pau, Segura-Bayona, Sandra, Koole, Wouter, van Heteren, Jane T, Dewar, James M, Tijsterman, Marcel, Knipscheer, Puck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282361/
https://www.ncbi.nlm.nih.gov/pubmed/25193968
http://dx.doi.org/10.15252/embj.201488663