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FANCJ promotes DNA synthesis through G-quadruplex structures
Our genome contains many G-rich sequences, which have the propensity to fold into stable secondary DNA structures called G4 or G-quadruplex structures. These structures have been implicated in cellular processes such as gene regulation and telomere maintenance. However, G4 sequences are prone to mut...
Autores principales: | Castillo Bosch, Pau, Segura-Bayona, Sandra, Koole, Wouter, van Heteren, Jane T, Dewar, James M, Tijsterman, Marcel, Knipscheer, Puck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282361/ https://www.ncbi.nlm.nih.gov/pubmed/25193968 http://dx.doi.org/10.15252/embj.201488663 |
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