The effect of relaxin on the musculoskeletal system

Relaxin is a hormone structurally related to insulin and insulin-like growth factor, which exerts its regulatory effect on the musculoskeletal and other systems through binding to its receptor in various tissues, mediated by different signaling pathways. Relaxin alters the properties of cartilage an...

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Autores principales: Dehghan, F, Haerian, B S, Muniandy, S, Yusof, A, Dragoo, J L, Salleh, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Online Only Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282454/
https://www.ncbi.nlm.nih.gov/pubmed/24283470
http://dx.doi.org/10.1111/sms.12149
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author Dehghan, F
Haerian, B S
Muniandy, S
Yusof, A
Dragoo, J L
Salleh, N
author_facet Dehghan, F
Haerian, B S
Muniandy, S
Yusof, A
Dragoo, J L
Salleh, N
author_sort Dehghan, F
collection PubMed
description Relaxin is a hormone structurally related to insulin and insulin-like growth factor, which exerts its regulatory effect on the musculoskeletal and other systems through binding to its receptor in various tissues, mediated by different signaling pathways. Relaxin alters the properties of cartilage and tendon by activating collagenase. This hormone is also involved in bone remodeling and healing of injured ligaments and skeletal muscle. In this review, we have summarized the literature on the effect of relaxin in musculoskeletal system to provide a broad perspective for future studies in this field.
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spelling pubmed-42824542015-01-15 The effect of relaxin on the musculoskeletal system Dehghan, F Haerian, B S Muniandy, S Yusof, A Dragoo, J L Salleh, N Scand J Med Sci Sports Online Only Articles Relaxin is a hormone structurally related to insulin and insulin-like growth factor, which exerts its regulatory effect on the musculoskeletal and other systems through binding to its receptor in various tissues, mediated by different signaling pathways. Relaxin alters the properties of cartilage and tendon by activating collagenase. This hormone is also involved in bone remodeling and healing of injured ligaments and skeletal muscle. In this review, we have summarized the literature on the effect of relaxin in musculoskeletal system to provide a broad perspective for future studies in this field. BlackWell Publishing Ltd 2014-08 2013-11-28 /pmc/articles/PMC4282454/ /pubmed/24283470 http://dx.doi.org/10.1111/sms.12149 Text en © 2013 The Authors. Scandinavian Journal of Medicine & Science in Sports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Online Only Articles
Dehghan, F
Haerian, B S
Muniandy, S
Yusof, A
Dragoo, J L
Salleh, N
The effect of relaxin on the musculoskeletal system
title The effect of relaxin on the musculoskeletal system
title_full The effect of relaxin on the musculoskeletal system
title_fullStr The effect of relaxin on the musculoskeletal system
title_full_unstemmed The effect of relaxin on the musculoskeletal system
title_short The effect of relaxin on the musculoskeletal system
title_sort effect of relaxin on the musculoskeletal system
topic Online Only Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282454/
https://www.ncbi.nlm.nih.gov/pubmed/24283470
http://dx.doi.org/10.1111/sms.12149
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