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Hypoxia Modulates the Phenotype of Osteoblasts Isolated From Knee Osteoarthritis Patients, Leading to Undermineralized Bone Nodule Formation
OBJECTIVE: To investigate the role of hypoxia in the pathology of osteoarthritic (OA) bone by exploring its effect on the phenotype of isolated primary osteoblasts from patients with knee OA. METHODS: OA bone samples were collected at the time of elective joint replacement surgery for knee or hip OA...
Autores principales: | Chang, Joan, Jackson, Sonya G, Wardale, John, Jones, Simon W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282481/ https://www.ncbi.nlm.nih.gov/pubmed/24574272 http://dx.doi.org/10.1002/art.38403 |
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