Specificity of a protein–protein interface: Local dynamics direct substrate recognition of effector caspases

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Proteases are prototypes of multispecific protein–protein interfaces. Proteases recognize and cleave protein and peptide substrates at a well-defined position in a substrate binding groove and a plethora of experimental techniques provide insights into their substrate recognition. We investigate the...

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Detalles Bibliográficos
Autores principales: Fuchs, Julian E, von Grafenstein, Susanne, Huber, Roland G, Wallnoefer, Hannes G, Liedl, Klaus R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282588/
https://www.ncbi.nlm.nih.gov/pubmed/24085488
http://dx.doi.org/10.1002/prot.24417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282588/
https://www.ncbi.nlm.nih.gov/pubmed/24085488
http://dx.doi.org/10.1002/prot.24417

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