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ImmunoGlobulin galaxy (IGGalaxy) for simple determination and quantitation of immunoglobulin heavy chain rearrangements from NGS
BACKGROUND: Sequence analysis of immunoglobulin heavy chain (IGH) gene rearrangements and frequency analysis is a powerful tool for studying the immune repertoire, immune responses and immune dysregulation in health and disease. The challenge is to provide user friendly, secure and reproducible anal...
Autores principales: | Moorhouse, Michael J, van Zessen, David, IJspeert, Hanna, Hiltemann, Saskia, Horsman, Sebastian, van der Spek, Peter J, van der Burg, Mirjam, Stubbs, Andrew P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282729/ https://www.ncbi.nlm.nih.gov/pubmed/25495099 http://dx.doi.org/10.1186/s12865-014-0059-7 |
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