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ImmunoGlobulin galaxy (IGGalaxy) for simple determination and quantitation of immunoglobulin heavy chain rearrangements from NGS

BACKGROUND: Sequence analysis of immunoglobulin heavy chain (IGH) gene rearrangements and frequency analysis is a powerful tool for studying the immune repertoire, immune responses and immune dysregulation in health and disease. The challenge is to provide user friendly, secure and reproducible anal...

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Detalles Bibliográficos
Autores principales: Moorhouse, Michael J, van Zessen, David, IJspeert, Hanna, Hiltemann, Saskia, Horsman, Sebastian, van der Spek, Peter J, van der Burg, Mirjam, Stubbs, Andrew P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282729/
https://www.ncbi.nlm.nih.gov/pubmed/25495099
http://dx.doi.org/10.1186/s12865-014-0059-7

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