Cytotoxic T lymphocyte lysis of HTLV-1 infected cells is limited by weak HBZ protein expression, but non-specifically enhanced on induction of Tax expression

BACKGROUND: Immunogenetic evidence indicates that cytotoxic T lymphocytes (CTLs) specific for the weak CTL antigen HBZ limit HTLV-1 proviral load in vivo, whereas there is no clear relationship between the proviral load and the frequency of CTLs specific for the immunodominant antigen Tax. In vivo,...

Descripción completa

Detalles Bibliográficos
Autores principales: Rowan, Aileen G, Suemori, Koichiro, Fujiwara, Hiroshi, Yasukawa, Masaki, Tanaka, Yuetsu, Taylor, Graham P, Bangham, Charles RM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282740/
https://www.ncbi.nlm.nih.gov/pubmed/25499803
http://dx.doi.org/10.1186/s12977-014-0116-6

Ejemplares similares

Ejemplares similares