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Functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: Primary malignant melanoma in the base of the tongue
Primary malignant melanoma of the oral cavity is a rare neoplasm, especially on the tongue. We report a case of mucosal melanoma at the base of the tongue, an extremely rare location (only about 30 cases have been reported in literature). The extension study doesn´t revealed distant metastatic lesio...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282919/ https://www.ncbi.nlm.nih.gov/pubmed/25593674 http://dx.doi.org/10.4317/jced.51606 |
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author | Rubio-Correa, Isidoro Manzano-Solo-de-Zaldívar, Damián Moreno-Sánchez, Manuel Hernández-Vila, Cristina Ramírez-Pérez, Francisco-Alejandro González-Ballester, David Ruíz-Laza, Luis González-García, Raúl Monje-Gil, Florencio |
author_facet | Rubio-Correa, Isidoro Manzano-Solo-de-Zaldívar, Damián Moreno-Sánchez, Manuel Hernández-Vila, Cristina Ramírez-Pérez, Francisco-Alejandro González-Ballester, David Ruíz-Laza, Luis González-García, Raúl Monje-Gil, Florencio |
author_sort | Rubio-Correa, Isidoro |
collection | PubMed |
description | Primary malignant melanoma of the oral cavity is a rare neoplasm, especially on the tongue. We report a case of mucosal melanoma at the base of the tongue, an extremely rare location (only about 30 cases have been reported in literature). The extension study doesn´t revealed distant metastatic lesions. The patient was treated by subtotal glossectomy and bilateral functional neck dissection. Tongue is one of the most difficult structures to reconstruct, because of their central role in phonation, swallowing and airway protection. The defect was reconstructed with anterolateral thigh free flap. Surgical treatment was supplemented with adjuvant immunotherapy. The post-operative period was uneventful. At present, 24 months after surgery, patient is asymptomatic, there isn´t evidence of recurrence of melanoma and he hasn´t any difficulty in swallowing or phonation. Key words:Malignant mucosal melanoma, anterolateral thigh free flap, phonation, swallowing. |
format | Online Article Text |
id | pubmed-4282919 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-42829192015-01-15 Functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: Primary malignant melanoma in the base of the tongue Rubio-Correa, Isidoro Manzano-Solo-de-Zaldívar, Damián Moreno-Sánchez, Manuel Hernández-Vila, Cristina Ramírez-Pérez, Francisco-Alejandro González-Ballester, David Ruíz-Laza, Luis González-García, Raúl Monje-Gil, Florencio J Clin Exp Dent Case Report Primary malignant melanoma of the oral cavity is a rare neoplasm, especially on the tongue. We report a case of mucosal melanoma at the base of the tongue, an extremely rare location (only about 30 cases have been reported in literature). The extension study doesn´t revealed distant metastatic lesions. The patient was treated by subtotal glossectomy and bilateral functional neck dissection. Tongue is one of the most difficult structures to reconstruct, because of their central role in phonation, swallowing and airway protection. The defect was reconstructed with anterolateral thigh free flap. Surgical treatment was supplemented with adjuvant immunotherapy. The post-operative period was uneventful. At present, 24 months after surgery, patient is asymptomatic, there isn´t evidence of recurrence of melanoma and he hasn´t any difficulty in swallowing or phonation. Key words:Malignant mucosal melanoma, anterolateral thigh free flap, phonation, swallowing. Medicina Oral S.L. 2014-10-01 /pmc/articles/PMC4282919/ /pubmed/25593674 http://dx.doi.org/10.4317/jced.51606 Text en Copyright: © 2014 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Rubio-Correa, Isidoro Manzano-Solo-de-Zaldívar, Damián Moreno-Sánchez, Manuel Hernández-Vila, Cristina Ramírez-Pérez, Francisco-Alejandro González-Ballester, David Ruíz-Laza, Luis González-García, Raúl Monje-Gil, Florencio Functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: Primary malignant melanoma in the base of the tongue |
title | Functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: Primary malignant melanoma in the base of the tongue |
title_full | Functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: Primary malignant melanoma in the base of the tongue |
title_fullStr | Functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: Primary malignant melanoma in the base of the tongue |
title_full_unstemmed | Functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: Primary malignant melanoma in the base of the tongue |
title_short | Functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: Primary malignant melanoma in the base of the tongue |
title_sort | functional reconstruction after subtotal glossectomy in the surgical treatment of an uncommon and aggressive neoplasm in this location: primary malignant melanoma in the base of the tongue |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282919/ https://www.ncbi.nlm.nih.gov/pubmed/25593674 http://dx.doi.org/10.4317/jced.51606 |
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