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PTEN Loss is Associated with Upgrading of Prostate Cancer from Biopsy to Radical Prostatectomy

When distinguishing between indolent and potentially harmful prostate cancers, the Gleason score is the most important variable, but may be inaccurate in biopsies due to tumor under-sampling. This study investigated whether a molecular feature, PTEN protein loss, could help identify which Gleason sc...

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Detalles Bibliográficos
Autores principales:	Lotan, Tamara L., Carvalho, Filipe LF., Peskoe, Sarah B., Hicks, Jessica L., Good, Jennifer, Fedor, Helen, Humphreys, Elizabeth, Han, Misop, Platz, Elizabeth A., Squire, Jeremy A., De Marzo, Angelo M., Berman, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282985/ https://www.ncbi.nlm.nih.gov/pubmed/24993522 http://dx.doi.org/10.1038/modpathol.2014.85

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