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Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes

Antibodies are critical for defence against a variety of microbes but may also be pathogenic in some autoimmune diseases. Many effector functions of antibody are mediated by Fcγ receptors (FcγRs), which are found on most immune cells, including dendritic cells (DCs). DCs are important antigen presen...

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Detalles Bibliográficos
Autores principales: Clatworthy, Menna R., Aronin, Caren E. Petrie, Mathews, Rebeccah J., Morgan, Nicole, Smith, Kenneth G.C., Germain, Ronald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283039/
https://www.ncbi.nlm.nih.gov/pubmed/25384086
http://dx.doi.org/10.1038/nm.3709