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Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

Cancer genomes accumulate numerous genetic and epigenetic modifications. Yet, human cellular transformation can be accomplished by a few genetically defined elements. These elements activate key pathways required to support replicative immortality and anchorage independent growth, a predictor of tum...

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Detalles Bibliográficos
Autores principales:	Hong, Xin, Nguyen, Hung Thanh, Chen, Qingfeng, Zhang, Rui, Hagman, Zandra, Voorhoeve, P Mathijs, Cohen, Stephen M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283404/ https://www.ncbi.nlm.nih.gov/pubmed/25180228 http://dx.doi.org/10.15252/embj.201489385

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