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Succinate Overproduction: A Case Study of Computational Strain Design Using a Comprehensive Escherichia coli Kinetic Model

Computational strain-design prediction accuracy has been the focus for many recent efforts through the selective integration of kinetic information into metabolic models. In general, kinetic model prediction quality is determined by the range and scope of genetic and/or environmental perturbations u...

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Detalles Bibliográficos
Autores principales: Khodayari, Ali, Chowdhury, Anupam, Maranas, Costas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283520/
https://www.ncbi.nlm.nih.gov/pubmed/25601910
http://dx.doi.org/10.3389/fbioe.2014.00076