Depending on the stage of hepatosteatosis, p53 causes apoptosis primarily through either DRAM-induced autophagy or BAX

BACKGROUND & AIMS: Apoptosis mediated by p53 plays a pathological role in the progression of hepatosteatosis. It is noteworthy that p53 can promote the expression of damage-regulated autophagy modulator (DRAM), an inducer of autophagy-mediated apoptosis. However, the relationship between p53-med...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Kai, Lou, Jinli, Wen, Tao, Yin, Jiming, Xu, Bin, Ding, Wei, Wang, Anna, Liu, Daojie, Zhang, Chao, Chen, Dexi, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283711/
https://www.ncbi.nlm.nih.gov/pubmed/23875779
http://dx.doi.org/10.1111/liv.12238

Ejemplares similares

Ejemplares similares