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Tumor-specific CD4(+) T cells maintain effector and memory tumor-specific CD8(+) T cells

Immunotherapies that augment antitumor T cells have had recent success for treating patients with cancer. Here we examined whether tumor-specific CD4(+) T cells enhance CD8(+) T-cell adoptive immunotherapy in a lymphopenic environment. Our model employed physiological doses of tyrosinase-related pro...

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Detalles Bibliográficos
Autores principales:	Church, Sarah E, Jensen, Shawn M, Antony, Paul A, Restifo, Nicholas P, Fox, Bernard A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Cellular Immune Response
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283993/ https://www.ncbi.nlm.nih.gov/pubmed/24114780 http://dx.doi.org/10.1002/eji.201343718

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