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Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity
H5N1 avian influenza is a significant global concern with the potential to become the next pandemic threat. Recombinant subunit vaccines are an attractive alternative for pandemic vaccines compared to traditional vaccine technologies. In particular, polyanhydride nanoparticles encapsulating subunit...
Autores principales: | Ross, Kathleen A, Loyd, Hyelee, Wu, Wuwei, Huntimer, Lucas, Ahmed, Shaheen, Sambol, Anthony, Broderick, Scott, Flickinger, Zachary, Rajan, Krishna, Bronich, Tatiana, Mallapragada, Surya, Wannemuehler, Michael J, Carpenter, Susan, Narasimhan, Balaji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284014/ https://www.ncbi.nlm.nih.gov/pubmed/25565816 http://dx.doi.org/10.2147/IJN.S72264 |
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