Cargando…

Targeting DNA G-Quadruplexes with Helical Small Molecules

We previously identified quinoline-based oligoamide helical foldamers and a trimeric macrocycle as selective ligands of DNA quadruplexes. Their helical structures might permit targeting of the backbone loops and grooves of G-quadruplexes instead of the G-tetrads. Given the vast array of morphologies...

Descripción completa

Detalles Bibliográficos
Autores principales:	Müller, Sebastian, Laxmi-Reddy, Katta, Jena, Prakrit V, Baptiste, Benoit, Dong, Zeyuan, Godde, Frédéric, Ha, Taekjip, Rodriguez, Raphaël, Balasubramanian, Shankar, Huc, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2014
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284101/ https://www.ncbi.nlm.nih.gov/pubmed/25256604 http://dx.doi.org/10.1002/cbic.201402439

Ejemplares similares

G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic
por: Jena, Prakrit V., et al.
Publicado: (2009)

Single molecule conformational analysis of DNA G-quadruplexes
por: Shirude, Pravin S., et al.
Publicado: (2008)

Helical Polycarbodiimide Cloaking of Carbon Nanotubes Enables Inter-Nanotube Exciton Energy Transfer Modulation
por: Budhathoki-Uprety, Januka, et al.
Publicado: (2014)

Kinetic Target‐Guided Synthesis of Small‐Molecule G‐Quadruplex Stabilizers
por: Pomeislová, Alice, et al.
Publicado: (2020)

Experimental approaches to identify cellular G-quadruplex structures and functions
por: Di Antonio, Marco, et al.
Publicado: (2012)

Prevalence of quadruplexes in the human genome
por: Huppert, Julian L., et al.
Publicado: (2005)

Discrete Stacked Dimers of Aromatic Oligoamide Helices
por: Bindl, Daniel, et al.
Publicado: (2022)

Translation of Rod-Like Template Sequences into Homochiral Assemblies of Stacked Helical Oligomers
por: Gan, Quan, et al.
Publicado: (2017)

Differential Peptide Multi‐Macrocyclizations at the Surface of a Helical Foldamer Template
por: Dengler, Sebastian, et al.
Publicado: (2022)

Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex**
por: Yangyuoru, Philip M, et al.
Publicado: (2015)

Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex**
por: Yangyuoru, Philip M, et al.
Publicado: (2015)

The Structure and Function of DNA G-Quadruplexes
por: Spiegel, Jochen, et al.
Publicado: (2020)

Single-molecule visualisation of DNA G-quadruplex formation in live cells
por: Di Antonio, Marco, et al.
Publicado: (2020)

Aromatic Foldamer Helices as α‐Helix Extended Surface Mimetics
por: Zwillinger, Márton, et al.
Publicado: (2020)

G-quadruplexes in promoters throughout the human genome
por: Huppert, Julian L., et al.
Publicado: (2007)

G-quadruplexes in promoters throughout the human genome
por: Huppert, Julian L., et al.
Publicado: (2007)

Targeted Detection of G-Quadruplexes in Cellular RNAs**
por: Kwok, Chun Kit, et al.
Publicado: (2015)

Development of an Efficient G‐Quadruplex‐Stabilised Thrombin‐Binding Aptamer Containing a Three‐Carbon Spacer Molecule
por: Aaldering, Lukas J., et al.
Publicado: (2017)

An RNA Hairpin to G-Quadruplex Conformational Transition
por: Bugaut, Anthony, et al.
Publicado: (2012)

G-quadruplexes: the beginning and end of UTRs
por: Huppert, Julian Leon, et al.
Publicado: (2008)

5′-UTR RNA G-quadruplexes: translation regulation and targeting
por: Bugaut, Anthony, et al.
Publicado: (2012)

Conformational interplay in hybrid peptide–helical aromatic foldamer macrocycles
por: Dengler, Sebastian, et al.
Publicado: (2021)

Directing the Self‐Assembly of Aromatic Foldamer Helices using Acridine Appendages and Metal Coordination
por: Wang, Jinhua, et al.
Publicado: (2022)

Unraveling helicase mechanisms one molecule at a time
por: Rasnik, Ivan, et al.
Publicado: (2006)

Selective RNAVersus DNA G-Quadruplex Targeting by In Situ Click Chemistry**
por: Di Antonio, Marco, et al.
Publicado: (2012)

Catechol Thioesters: Ligands for Hierarchically Formed Lithium‐Bridged Titanium(IV) Helicates and Helicate‐Based Switches
por: Kwamen, A. Carel N., et al.
Publicado: (2020)

Helically and Linearly Fused Rylenediimide‐Hexabenzocoronenes
por: Dusold, Carolin, et al.
Publicado: (2021)

Oligo‐Quinolylene–Vinylene Foldamers
por: Wang, Jinhua, et al.
Publicado: (2020)

Multi-dimensional charge transport in supramolecular helical foldamer assemblies
por: Méndez-Ardoy, Alejandro, et al.
Publicado: (2017)

Parallel Homochiral and Anti‐Parallel Heterochiral Hydrogen‐Bonding Interfaces in Multi‐Helical Abiotic Foldamers
por: Mazzier, Daniela, et al.
Publicado: (2019)

Hybrid Sequences that Express both Aromatic Amide and α‐Peptidic Folding Features
por: Hu, Xiaobo, et al.
Publicado: (2020)

High-affinity single and double helical pseudofoldaxanes with cationic guests
por: Zhong, Yulong, et al.
Publicado: (2023)

G-Quadruplex structures are stable and detectable in human genomic DNA
por: Lam, Enid Yi Ni, et al.
Publicado: (2013)

RNA versus DNA G‐Quadruplex: The Origin of Increased Stability
por: Zaccaria, Francesco, et al.
Publicado: (2018)

Hole Migration in Telomere‐Based Oligonucleotide Anions and G‐Quadruplexes
por: Li, Wen, et al.
Publicado: (2019)

Reprogramming the Mechanism of Action of Chlorambucil by Coupling to a G-Quadruplex Ligand
por: Di Antonio, Marco, et al.
Publicado: (2014)

Mind your tag in single-molecule measurements
por: Merino Urteaga, Raquel, et al.
Publicado: (2023)

Dinickel–Salphen Complexes as Binders of Human Telomeric Dimeric G‐Quadruplexes
por: Zhou, Chun‐Qiong, et al.
Publicado: (2017)

The Binding Pocket at the Interface of Multimeric Telomere G‐quadruplexes: Myth or Reality?
por: Manoli, Francesco, et al.
Publicado: (2021)

Preferential Nucleosome Occupancy at High Values of DNA Helical Rise
por: Pedone, Francesco, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ndst8v1fbj5p59nrhdhoko1di4