Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction

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The role of the RhoGTPase Rac1 in stabilizing mature endothelial adherens junctions (AJs) is not well understood. In this paper, using a photoactivatable probe to control Rac1 activity at AJs, we addressed the relationship between Rac1 and the dynamics of vascular endothelial cadherin (VE-cadherin)....

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Detalles Bibliográficos
Autores principales: Daneshjou, Nazila, Sieracki, Nathan, van Nieuw Amerongen, Geerten P., Conway, Daniel E., Schwartz, Martin A., Komarova, Yulia A., Malik, Asrar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284224/
https://www.ncbi.nlm.nih.gov/pubmed/25559184
http://dx.doi.org/10.1083/jcb.201409108
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