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Thyrotropin and Obesity: Increased Adipose Triglyceride Content Through Glycerol-3-Phosphate Acyltransferase 3

Epidemiological evidence indicates that thyrotropin (TSH) is positively correlated with the severity of obesity. However, the mechanism remains unclear. Here, we show that TSH promoted triglyceride (TG) synthesis in differentiated adipocytes in a thyroid hormone-independent manner. Mice with subclin...

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Detalles Bibliográficos
Autores principales: Ma, Shizhan, Jing, Fei, Xu, Chao, Zhou, Lingyan, Song, Yongfeng, Yu, Chunxiao, Jiang, Dongqing, Gao, Ling, Li, Yujie, Guan, Qingbo, Zhao, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284501/
https://www.ncbi.nlm.nih.gov/pubmed/25559747
http://dx.doi.org/10.1038/srep07633