The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation

The hallmark of enteropathogenic Escherichia coli (EPEC) infection is the formation of actin-rich pedestal-like structures, which are generated following phosphorylation of the bacterial effector Tir by cellular Src and Abl family tyrosine kinases. This leads to recruitment of the Nck–WIP–N-WASP com...

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Detalles Bibliográficos
Autores principales: Young, Joanna C., Clements, Abigail, Lang, Alexander E., Garnett, James A., Munera, Diana, Arbeloa, Ana, Pearson, Jaclyn, Hartland, Elizabeth L., Matthews, Stephen J., Mousnier, Aurelie, Barry, David J., Way, Michael, Schlosser, Andreas, Aktories, Klaus, Frankel, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284639/
https://www.ncbi.nlm.nih.gov/pubmed/25523213
http://dx.doi.org/10.1038/ncomms6887

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