Targeting β-catenin signaling for therapeutic intervention in MEN1-deficient pancreatic neuroendocrine tumours

Inactivating MEN1 mutations are the most common genetic defects present in sporadic and inherited pancreatic neuroendocrine tumours (PNETs). The lack of interventional therapies prompts us to explore the therapeutic approach of targeting β-catenin signalling in MEN1-mutant PNETs. Here we show the ME...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Xiuli, Cao, Yanan, Li, Feng, Su, Yutong, Li, Yanli, Peng, Ying, Cheng, Yulong, Zhang, Changxian, Wang, Weiqing, Ning, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284642/
https://www.ncbi.nlm.nih.gov/pubmed/25517963
http://dx.doi.org/10.1038/ncomms6809

Ejemplares similares

Ejemplares similares