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Slow unloading leads to DNA-bound β(2)-sliding clamp accumulation in live Escherichia coli cells
The ubiquitous sliding clamp facilitates processivity of the replicative polymerase and acts as a platform to recruit proteins involved in replication, recombination and repair. While the dynamics of the E. coli β(2)-sliding clamp have been characterized in vitro, its in vivo stoichiometry and dynam...
Autores principales: | Moolman, M. Charl, Krishnan, Sriram Tiruvadi, Kerssemakers, Jacob W. J., van den Berg, Aafke, Tulinski, Pawel, Depken, Martin, Reyes-Lamothe, Rodrigo, Sherratt, David J., Dekker, Nynke H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284645/ https://www.ncbi.nlm.nih.gov/pubmed/25520215 http://dx.doi.org/10.1038/ncomms6820 |
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