Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle

Lactation, hair development and homeothermy are characteristic evolutionary features that define mammals from other vertebrate species. Here we describe the discovery of two autosomal dominant mutations with antagonistic, pleiotropic effects on all three of these biological processes, mediated throu...

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Detalles Bibliográficos
Autores principales: Littlejohn, Mathew D., Henty, Kristen M., Tiplady, Kathryn, Johnson, Thomas, Harland, Chad, Lopdell, Thomas, Sherlock, Richard G., Li, Wanbo, Lukefahr, Steven D., Shanks, Bruce C., Garrick, Dorian J., Snell, Russell G., Spelman, Richard J., Davis, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284646/
https://www.ncbi.nlm.nih.gov/pubmed/25519203
http://dx.doi.org/10.1038/ncomms6861

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