Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2

The endodermal lining of the adult gastro-intestinal tract harbours stem cells that are responsible for the day-to-day regeneration of the epithelium. Stem cells residing in the pyloric glands of the stomach and in the small intestinal crypts differ in their differentiation programme and in the gene...

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Detalles Bibliográficos
Autores principales: Simmini, Salvatore, Bialecka, Monika, Huch, Meritxell, Kester, Lennart, van de Wetering, Marc, Sato, Toshiro, Beck, Felix, van Oudenaarden, Alexander, Clevers, Hans, Deschamps, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284662/
https://www.ncbi.nlm.nih.gov/pubmed/25500896
http://dx.doi.org/10.1038/ncomms6728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284662/
https://www.ncbi.nlm.nih.gov/pubmed/25500896
http://dx.doi.org/10.1038/ncomms6728

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