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Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2
The endodermal lining of the adult gastro-intestinal tract harbours stem cells that are responsible for the day-to-day regeneration of the epithelium. Stem cells residing in the pyloric glands of the stomach and in the small intestinal crypts differ in their differentiation programme and in the gene...
Autores principales: | Simmini, Salvatore, Bialecka, Monika, Huch, Meritxell, Kester, Lennart, van de Wetering, Marc, Sato, Toshiro, Beck, Felix, van Oudenaarden, Alexander, Clevers, Hans, Deschamps, Jacqueline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284662/ https://www.ncbi.nlm.nih.gov/pubmed/25500896 http://dx.doi.org/10.1038/ncomms6728 |
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