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Epigenetic regulation of Atrophin1 by lysine-specific demethylase 1 is required for cortical progenitor maintenance

Lysine-specific demethylase 1 (LSD1) is involved in gene regulation and development; however, its precise function, molecular targets and underlying mechanisms during development are poorly understood. Here we show that LSD1 is required for neuronal progenitor cell (NPC) maintenance during cortical...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Xu, Dan, Yuan, Ling, Sun, Yiming, Xu, Zhiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284801/
https://www.ncbi.nlm.nih.gov/pubmed/25519973
http://dx.doi.org/10.1038/ncomms6815