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Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature
Despite the inarguable relevance of p53 in cancer, genome-wide studies relating endogenous p53 activity to the expression of lncRNAs in human cells are still missing. Here, by integrating RNA-seq with p53 ChIP-seq analyses of a human cancer cell line under DNA damage, we define a high-confidence set...
Autores principales: | Sánchez, Yolanda, Segura, Victor, Marín-Béjar, Oskar, Athie, Alejandro, Marchese, Francesco P., González, Jovanna, Bujanda, Luis, Guo, Shuling, Matheu, Ander, Huarte, Maite |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284803/ https://www.ncbi.nlm.nih.gov/pubmed/25524025 http://dx.doi.org/10.1038/ncomms6812 |
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