Cargando…
TRPA1 is essential for the vascular response to environmental cold exposure
The cold-induced vascular response, consisting of vasoconstriction followed by vasodilatation, is critical for protecting the cutaneous tissues against cold injury. Whilst this physiological reflex response is historic knowledge, the mechanisms involved are unclear. Here by using a murine model of l...
Autores principales: | Aubdool, Aisah A., Graepel, Rabea, Kodji, Xenia, Alawi, Khadija M., Bodkin, Jennifer V., Srivastava, Salil, Gentry, Clive, Heads, Richard, Grant, Andrew D., Fernandes, Elizabeth S., Bevan, Stuart, Brain, Susan D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284811/ https://www.ncbi.nlm.nih.gov/pubmed/25501034 http://dx.doi.org/10.1038/ncomms6732 |
Ejemplares similares
-
TRPA1 activation leads to neurogenic vasodilatation: involvement of reactive oxygen nitrogen species in addition to CGRP and NO
por: Aubdool, Aisah A, et al.
Publicado: (2016) -
Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner
por: Fernandes, Elizabeth S., et al.
Publicado: (2016) -
Investigating the potential role of TRPA1 in locomotion and cardiovascular control during hypertension
por: Bodkin, Jennifer V, et al.
Publicado: (2014) -
Relevance of TRPA1 and TRPM8 channels as vascular sensors of cold in the cutaneous microvasculature
por: Pan, Y., et al.
Publicado: (2017) -
The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity
por: Gentry, Clive, et al.
Publicado: (2010)