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Design, synthesis, docking study and cytotoxic activity evaluation of some novel letrozole analogs
BACKGROUND: Breast cancer is the most common type of female cancer. One class of hormonal therapy for breast cancer drugs -non steroidal aromatase inhibitors- are triazole analogues. In this work, some derivatives of these drugs was designed and synthesized. All synthesized compounds were evaluated...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284924/ https://www.ncbi.nlm.nih.gov/pubmed/25539909 http://dx.doi.org/10.1186/s40199-014-0083-4 |