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Design, synthesis, docking study and cytotoxic activity evaluation of some novel letrozole analogs

BACKGROUND: Breast cancer is the most common type of female cancer. One class of hormonal therapy for breast cancer drugs -non steroidal aromatase inhibitors- are triazole analogues. In this work, some derivatives of these drugs was designed and synthesized. All synthesized compounds were evaluated...

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Detalles Bibliográficos
Autores principales:	Vosooghi, Mohsen, Firoozpour, Loghman, Rodaki, Abolfazl, Pordeli, Mahboobeh, Safavi, Maliheh, Ardestani, Sussan K, Dadgar, Armin, Asadipour, Ali, Moshafi, Mohammad Hassan, Foroumadi, Alireza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284924/ https://www.ncbi.nlm.nih.gov/pubmed/25539909 http://dx.doi.org/10.1186/s40199-014-0083-4

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