Cargando…

A Vertebral Artery Dissection with Basilar Artery Occlusion in a Child

This paper presents the case report of an 11-year-old boy with an acute dissection with thrombosis of the left vertebral artery and thrombosis of the basilar artery. The patient was treated with acute systemic thrombolysis, followed by intra-arterial thrombolysis, without any clinical improvement, s...

Descripción completa

Detalles Bibliográficos
Autores principales: Devue, Katleen, Van Ingelgem, Annemie, De Keukeleire, Katrien, De Leeuw, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284989/
https://www.ncbi.nlm.nih.gov/pubmed/25587466
http://dx.doi.org/10.1155/2014/706147
_version_ 1782351503915220992
author Devue, Katleen
Van Ingelgem, Annemie
De Keukeleire, Katrien
De Leeuw, Marc
author_facet Devue, Katleen
Van Ingelgem, Annemie
De Keukeleire, Katrien
De Leeuw, Marc
author_sort Devue, Katleen
collection PubMed
description This paper presents the case report of an 11-year-old boy with an acute dissection with thrombosis of the left vertebral artery and thrombosis of the basilar artery. The patient was treated with acute systemic thrombolysis, followed by intra-arterial thrombolysis, without any clinical improvement, showing left hemiplegia, bilateral clonus, hyperreflexia, and impaired consciousness. MRI indicated persistent thrombosis of the arteria basilaris with edema and ischemia of the right brainstem. Heparinization for 72 hours, followed by a two-week LMWH treatment and subsequent oral warfarin therapy, resulted in a lasting improvement of the symptoms. Vertebral artery dissection after minor trauma is rare in children. While acute basilar artery occlusion as a complication is even more infrequent, it is potentially fatal, which means that prompt diagnosis and treatment are imperative. The lack of class I recommendation guidelines for children regarding treatment of vertebral artery dissection and basilar artery occlusion means that initial and follow-up management both require a multidisciplinary approach to coordinate emergency, critical care, interventional radiology, and child neurology services.
format Online
Article
Text
id pubmed-4284989
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-42849892015-01-13 A Vertebral Artery Dissection with Basilar Artery Occlusion in a Child Devue, Katleen Van Ingelgem, Annemie De Keukeleire, Katrien De Leeuw, Marc Case Rep Emerg Med Case Report This paper presents the case report of an 11-year-old boy with an acute dissection with thrombosis of the left vertebral artery and thrombosis of the basilar artery. The patient was treated with acute systemic thrombolysis, followed by intra-arterial thrombolysis, without any clinical improvement, showing left hemiplegia, bilateral clonus, hyperreflexia, and impaired consciousness. MRI indicated persistent thrombosis of the arteria basilaris with edema and ischemia of the right brainstem. Heparinization for 72 hours, followed by a two-week LMWH treatment and subsequent oral warfarin therapy, resulted in a lasting improvement of the symptoms. Vertebral artery dissection after minor trauma is rare in children. While acute basilar artery occlusion as a complication is even more infrequent, it is potentially fatal, which means that prompt diagnosis and treatment are imperative. The lack of class I recommendation guidelines for children regarding treatment of vertebral artery dissection and basilar artery occlusion means that initial and follow-up management both require a multidisciplinary approach to coordinate emergency, critical care, interventional radiology, and child neurology services. Hindawi Publishing Corporation 2014 2014-12-23 /pmc/articles/PMC4284989/ /pubmed/25587466 http://dx.doi.org/10.1155/2014/706147 Text en Copyright © 2014 Katleen Devue et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Devue, Katleen
Van Ingelgem, Annemie
De Keukeleire, Katrien
De Leeuw, Marc
A Vertebral Artery Dissection with Basilar Artery Occlusion in a Child
title A Vertebral Artery Dissection with Basilar Artery Occlusion in a Child
title_full A Vertebral Artery Dissection with Basilar Artery Occlusion in a Child
title_fullStr A Vertebral Artery Dissection with Basilar Artery Occlusion in a Child
title_full_unstemmed A Vertebral Artery Dissection with Basilar Artery Occlusion in a Child
title_short A Vertebral Artery Dissection with Basilar Artery Occlusion in a Child
title_sort vertebral artery dissection with basilar artery occlusion in a child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284989/
https://www.ncbi.nlm.nih.gov/pubmed/25587466
http://dx.doi.org/10.1155/2014/706147
work_keys_str_mv AT devuekatleen avertebralarterydissectionwithbasilararteryocclusioninachild
AT vaningelgemannemie avertebralarterydissectionwithbasilararteryocclusioninachild
AT dekeukeleirekatrien avertebralarterydissectionwithbasilararteryocclusioninachild
AT deleeuwmarc avertebralarterydissectionwithbasilararteryocclusioninachild
AT devuekatleen vertebralarterydissectionwithbasilararteryocclusioninachild
AT vaningelgemannemie vertebralarterydissectionwithbasilararteryocclusioninachild
AT dekeukeleirekatrien vertebralarterydissectionwithbasilararteryocclusioninachild
AT deleeuwmarc vertebralarterydissectionwithbasilararteryocclusioninachild