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Asymmetric Carbamoyl Anion Additions to Chiral N-Phosphonyl Imines via the GAP Chemistry Process and Stereoselectivity Enrichments

[Image: see text] Carbamoyl anions were found to smoothly react with chiral N-phosphonyl imines in toluene at −78 °C to r.t. using LiHMDS as the base. Group-assisted purification (GAP) has been utilized to give the pure amides without using column chromatography or recrystallization. The asymmetric...

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Detalles Bibliográficos
Autores principales:	Seifert, Cole W., Pindi, Suresh, Li, Guigen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285137/ https://www.ncbi.nlm.nih.gov/pubmed/25458404 http://dx.doi.org/10.1021/jo5024443

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