Coxiella burnetii lipopolysaccharide blocks p38α-MAPK activation through the disruption of TLR-2 and TLR-4 association

To survive in macrophages, Coxiella burnetii hijacks the activation pathway of macrophages. Recently, we have demonstrated that C. burnetii, via its lipopolysaccharide (LPS), avoids the activation of p38α-MAPK through an antagonistic engagement of Toll-like receptor (TLR)-4. We investigated the fine...

Descripción completa

Detalles Bibliográficos
Autores principales: Conti, Filippo, Boucherit, Nicolas, Baldassarre, Veronica, Trouplin, Virginie, Toman, Rudolf, Mottola, Giovanna, Mege, Jean-Louis, Ghigo, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285172/
https://www.ncbi.nlm.nih.gov/pubmed/25610812
http://dx.doi.org/10.3389/fcimb.2014.00182

Ejemplares similares

Ejemplares similares