Trypanosoma brucei histone H1 inhibits RNA polymerase I transcription and is important for parasite fitness in vivo

Trypanosoma brucei is a unicellular parasite that causes sleeping sickness in humans. Most of its transcription is constitutive and driven by RNA polymerase II. RNA polymerase I (Pol I) transcribes not only ribosomal RNA genes, but also protein-encoding genes, including variant surface glycoproteins...

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Detalles Bibliográficos
Autores principales: Pena, Ana C, Pimentel, Mafalda R, Manso, Helena, Vaz-Drago, Rita, Pinto-Neves, Daniel, Aresta-Branco, Francisco, Rijo-Ferreira, Filipa, Guegan, Fabien, Pedro Coelho, Luis, Carmo-Fonseca, Maria, Barbosa-Morais, Nuno L, Figueiredo, Luisa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285223/
https://www.ncbi.nlm.nih.gov/pubmed/24946224
http://dx.doi.org/10.1111/mmi.12677

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