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Specific analogues uncouple transport, signalling, oligo-ubiquitination and endocytosis in the yeast Gap1 amino acid transceptor

The Saccharomyces cerevisiae amino acid transceptor Gap1 functions as receptor for signalling to the PKA pathway and concomitantly undergoes substrate-induced oligo-ubiquitination and endocytosis. We have identified specific amino acids and analogues that uncouple to certain extent signalling, trans...

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Detalles Bibliográficos
Autores principales:	Van Zeebroeck, Griet, Rubio-Texeira, Marta, Schothorst, Joep, Thevelein, Johan M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285233/ https://www.ncbi.nlm.nih.gov/pubmed/24852066 http://dx.doi.org/10.1111/mmi.12654

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