Oseltamivir-Resistant Influenza A(H1N1)pdm09 Viruses, United States, 2013–14

We report characteristics of oseltamivir-resistant influenza A(H1N1)pdm09 viruses and patients infected with these viruses in the United States. During 2013–14, fifty-nine (1.2%) of 4,968 analyzed US influenza A(H1N1)pdm09 viruses had the H275Y oseltamivir resistance–conferring neuraminidase substit...

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Detalles Bibliográficos
Autores principales: Okomo-Adhiambo, Margaret, Fry, Alicia M., Su, Su, Nguyen, Ha T., Elal, Anwar Abd, Negron, Elizabeth, Hand, Julie, Garten, Rebecca J., Barnes, John, Xiyan, Xu, Villanueva, Julie M., Gubareva, Larisa V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285251/
https://www.ncbi.nlm.nih.gov/pubmed/25532050
http://dx.doi.org/10.3201/eid2101.141006
Descripción
Sumario:We report characteristics of oseltamivir-resistant influenza A(H1N1)pdm09 viruses and patients infected with these viruses in the United States. During 2013–14, fifty-nine (1.2%) of 4,968 analyzed US influenza A(H1N1)pdm09 viruses had the H275Y oseltamivir resistance–conferring neuraminidase substitution. Our results emphasize the need for local surveillance for neuraminidase inhibitor susceptibility among circulating influenza viruses.

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