Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR...

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Detalles Bibliográficos
Autores principales: Gayet-Ageron, Angèle, Sednaoui, Patrice, Lautenschlager, Stephan, Ferry, Tristan, Toutous-Trellu, Laurence, Cavassini, Matthias, Yassir, Fatima, Martinez de Tejada, Begoña, Emonet, Stéphane, Combescure, Christophe, Schrenzel, Jacques, Perneger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285282/
https://www.ncbi.nlm.nih.gov/pubmed/25531672
http://dx.doi.org/10.3201/eid2101.140790
Descripción
Sumario:Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.

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