Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis

Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR...

Descripción completa

Detalles Bibliográficos
Autores principales: Gayet-Ageron, Angèle, Sednaoui, Patrice, Lautenschlager, Stephan, Ferry, Tristan, Toutous-Trellu, Laurence, Cavassini, Matthias, Yassir, Fatima, Martinez de Tejada, Begoña, Emonet, Stéphane, Combescure, Christophe, Schrenzel, Jacques, Perneger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285282/
https://www.ncbi.nlm.nih.gov/pubmed/25531672
http://dx.doi.org/10.3201/eid2101.140790
_version_ 1782351562686857216
author Gayet-Ageron, Angèle
Sednaoui, Patrice
Lautenschlager, Stephan
Ferry, Tristan
Toutous-Trellu, Laurence
Cavassini, Matthias
Yassir, Fatima
Martinez de Tejada, Begoña
Emonet, Stéphane
Combescure, Christophe
Schrenzel, Jacques
Perneger, Thomas
author_facet Gayet-Ageron, Angèle
Sednaoui, Patrice
Lautenschlager, Stephan
Ferry, Tristan
Toutous-Trellu, Laurence
Cavassini, Matthias
Yassir, Fatima
Martinez de Tejada, Begoña
Emonet, Stéphane
Combescure, Christophe
Schrenzel, Jacques
Perneger, Thomas
author_sort Gayet-Ageron, Angèle
collection PubMed
description Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.
format Online
Article
Text
id pubmed-4285282
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-42852822015-01-12 Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis Gayet-Ageron, Angèle Sednaoui, Patrice Lautenschlager, Stephan Ferry, Tristan Toutous-Trellu, Laurence Cavassini, Matthias Yassir, Fatima Martinez de Tejada, Begoña Emonet, Stéphane Combescure, Christophe Schrenzel, Jacques Perneger, Thomas Emerg Infect Dis Dispatch Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM. Centers for Disease Control and Prevention 2015-01 /pmc/articles/PMC4285282/ /pubmed/25531672 http://dx.doi.org/10.3201/eid2101.140790 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Gayet-Ageron, Angèle
Sednaoui, Patrice
Lautenschlager, Stephan
Ferry, Tristan
Toutous-Trellu, Laurence
Cavassini, Matthias
Yassir, Fatima
Martinez de Tejada, Begoña
Emonet, Stéphane
Combescure, Christophe
Schrenzel, Jacques
Perneger, Thomas
Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_full Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_fullStr Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_full_unstemmed Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_short Use of Treponema pallidum PCR in Testing of Ulcers for Diagnosis of Primary Syphilis
title_sort use of treponema pallidum pcr in testing of ulcers for diagnosis of primary syphilis
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285282/
https://www.ncbi.nlm.nih.gov/pubmed/25531672
http://dx.doi.org/10.3201/eid2101.140790
work_keys_str_mv AT gayetageronangele useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT sednaouipatrice useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT lautenschlagerstephan useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT ferrytristan useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT toutoustrellulaurence useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT cavassinimatthias useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT yassirfatima useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT martinezdetejadabegona useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT emonetstephane useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT combescurechristophe useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT schrenzeljacques useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis
AT pernegerthomas useoftreponemapallidumpcrintestingofulcersfordiagnosisofprimarysyphilis

Ejemplares similares