Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), α-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro...

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Detalles Bibliográficos
Autores principales: Abdel-Sattar, Essam, Abou-Hussein, Dina, Petereit, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285643/
https://www.ncbi.nlm.nih.gov/pubmed/25598629
http://dx.doi.org/10.4103/0974-8490.147136
Descripción
Sumario:Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), α-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.

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