Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), α-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro...

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Autores principales: Abdel-Sattar, Essam, Abou-Hussein, Dina, Petereit, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285643/
https://www.ncbi.nlm.nih.gov/pubmed/25598629
http://dx.doi.org/10.4103/0974-8490.147136
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author Abdel-Sattar, Essam
Abou-Hussein, Dina
Petereit, Frank
author_facet Abdel-Sattar, Essam
Abou-Hussein, Dina
Petereit, Frank
author_sort Abdel-Sattar, Essam
collection PubMed
description Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), α-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.
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spelling pubmed-42856432015-01-16 Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia Abdel-Sattar, Essam Abou-Hussein, Dina Petereit, Frank Pharmacognosy Res Original Article Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), α-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4285643/ /pubmed/25598629 http://dx.doi.org/10.4103/0974-8490.147136 Text en Copyright: © Pharmacognosy Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Abdel-Sattar, Essam
Abou-Hussein, Dina
Petereit, Frank
Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia
title Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia
title_full Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia
title_fullStr Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia
title_full_unstemmed Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia
title_short Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia
title_sort chemical constituents from the leaves of euphorbia ammak growing in saudi arabia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285643/
https://www.ncbi.nlm.nih.gov/pubmed/25598629
http://dx.doi.org/10.4103/0974-8490.147136
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